There are four variations of Keno:

The following tips apply to all variations of keno:
Just because a number hasn't come up in a draw, doesn't mean that it's more likely to come up in the next. No particular number is more probable to come up than another; they're all in the same container and thus, have the same odds of being drawn.

There is no certain combination of numbers that is more likely to win.
1, 2, 3, 4, 5 is just as likely to come up as 6, 39, 24, 80, 44. The first combination is just as unique as the second even though the first seems to be more special because the numbers are in sequence.

Keep your numbers the same regardless of what they are until you hit large on them. You will always come out ahead at least once. Since the chances of catching a certain combination are the same as another, playing the same numbers increases the chance of catching them.

When playing online or video keno, get a feel of the game first. It's virtually impossible to simulate true randomness electronically. Because the computer uses different algorithms to imitate a random draw, playing your numbers in patterns instead of spreading them out all over can sometimes work to your advantage.